<p>The Association Between Normal BMI With Central Adiposity And Proinflammatory Potential Immunoglobulin G N-Glycosylation</p>
نویسندگان
چکیده
منابع مشابه
A Case of Bruton’s Disease with Normal Immunoglobulin G Level
X-linked agamaglobulinemia (XLA) or Bruton’s disease is a genetic disease resulting from a mutation in the Bruton’s tyrosine kinase (Btk) gene. This mutation leads to B cell arrest during differentiation (1). This disease was first described by Ogden Bruton in 1952 (2). Approximately 85% of the affected subjects are male (3). This disorder is inherited as an X-linked recessive trait. Carrier fe...
متن کاملThe Association between Central Adiposity and Autonomic Dysfunction in Obesity
OBJECTIVE To determine the relationship between central adiposity parameters and autonomic nervous system (ANS) dysfunction. SUBJECTS AND METHODS The study included 114 obese individuals without any cardiovascular risk factors. Weight (in kg), height (in m), and waist circumference (WC; in cm) were measured and body mass index was calculated. Echocardiographic examination was performed to mea...
متن کاملInflammatory Bowel Disease Associates with Proinflammatory Potential of the Immunoglobulin G Glycome
BACKGROUND Glycobiology is an underexplored research area in inflammatory bowel disease (IBD), and glycans are relevant to many etiological mechanisms described in IBD. Alterations in N-glycans attached to the immunoglobulin G (IgG) Fc fragment can affect molecular structure and immunological function. Recent genome-wide association studies reveal pleiotropy between IBD and IgG glycosylation. T...
متن کاملThe Association Between Glycosylation of Immunoglobulin G and Hypertension
More than half of all known proteins, and almost all membrane and extra-cellular proteins have oligosaccharide structures or glycans attached to them. Defects in glycosylation pathways are directly involved in at least 30 severe human diseases.A multiple center cross-sectional study (China, Croatia, and Scotland) was carried out to investigate the possible association between hypertension and I...
متن کاملa case of bruton’s disease with normal immunoglobulin g level
x-linked agamaglobulinemia (xla) or bruton’s disease is a genetic disease resulting from a mutation in the bruton’s tyrosine kinase (btk) gene. this mutation leads to b cell arrest during differentiation (1). this disease was first described by ogden bruton in 1952 (2). approximately 85% of the affected subjects are male (3). this disorder is inherited as an x-linked recessive trait. carrier fe...
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ژورنال
عنوان ژورنال: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
سال: 2019
ISSN: 1178-7007
DOI: 10.2147/dmso.s216318